Nov 13, 2025 · HK1 (Hexokinase 1) is a Protein Coding gene. Diseases associated with HK1 include Anemia, Congenital, Nonspherocytic Hemolytic, 5 and Neuropathy, Hereditary Motor …

Hexokinase I, also known as hexokinase A and HK1, is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. Hexokinases phosphorylate glucose to produce glucose-6 …

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Jul 6, 2025 · Gene target information for HK1 - hexokinase 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Four different forms of hexokinase, designated type HK1, HK2 (601125), HK3 (142570), and HK4 (138079), encoded by different genes, are present in mammalian tissues.

HK1 is the dominant hexokinase enzyme in the brain and is predominantly bound to the outer mitochondrial membrane, where it catalyzes the phosphorylation of glucose to glucose-6 …

Aug 8, 2022 · Hexokinase (HK)-1 mitochondrial-binding mechanisms and consequential physiological relevance remain unclear. Recently, De Jesus et al. studied myeloid cells with …

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Th is gene encodes a ubiquitous form of hexokinase which …

The evaluation of individuals with Coombs-negative chronic hemolysis

Feb 9, 2025 · Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants …